The innovation in synthetic methodologies, in terms of selectivity, availability of starting materials, functional-group tolerance, operational simplicity and environmental sustainability, is fundamental to the art of organic synthesis. Transition-metal catalysis significantly contributes to the development of organic chemistry in the past few decades. Gold, silver, and copper, so-called “coinage metals”, exhibit interesting catalytic activities in organic synthesis. Unlike the long-term studies on copper catalysis and the “Gold Rush” over the past decade, silver salts have long been considered to possess low catalytic efficiency and most typically they are used as either cocatalysts or Lewis acids. In the last years, silver catalysis has been emerging as an active field in the frontier of organic synthesis, especially, its unique catalytic activity continue to be discovered, which provides the opportunity for the innovation in synthetic methodologies. Currently, our research group focused primarily in the field of silver catalysis, exploring its unique catalytic performance and developing new organic reactions. The concerns include:
1. Silver catalyzed coupling reactions.
2. Silver catalysis in alkyne and isocyanide chemistry.
3. Silver catalyzed transfer reactions of carbene, nitrene.